Fig. 1: Cells, bearing a mutation in the BAR1 gene leading to high pheromone sensitivity, were incubated with 1 μM α - factor for induction of the “Shmoo” - phenotype
Fig. 2: Cell-cycle arrest of a-cells with a bar1 mutation due to α- factor. Cells were incubated in the presence of 10 μM (upper panel) and 50 μM (lower panel) α - factor on a filter plate. Growth is inhibited due to the cell - cycle arrest.